drugset / Trial / NCT01185119
Effect of GLP-1 on Glucose Metabolism in CNS Assessed by PET
RandomizedCrossoverQuadruple-blindBasic science
Summary
10 healthy men will be PET-scanned (CNS) twice in random order with infusions of placebo or Native GLP-1 during hyperglycemic clamp to uncover the metabolic effects of GLP-1 in perspectives of intervention of macrovascular late diabetic pathology such as stroke and AMI. Earlier studies have revealed tendencies towards steady glucose metabolism in the CNS despite fluctuations in blood sugar when infusing native GLP-1.
Timeline
- Start
- 2010-06
- Primary completion
- 2010-12
- Completion
- 2011-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Beinaglutide | Protein / enzyme biologic | 1.2 unknown | Other |
Indications
No indication recorded.