PK Switch Efavirenz to Maraviroc in Patients Initially Suppressed on an Efavirenz-containing Regimen

Summary

The purpose of the study aims is to help determine whether it is safe to change directly from efavirenz to maraviroc in patients who are stable on an efavirenz-containing regimen. The pharmacokinetics (drug levels) of efavirenz and maraviroc when efavirenz is stopped and maraviroc is started will be assessed. Both the study patients and the study team will know which treatment is being taken at all times in the study.

Timeline

Start

2010-01

Primary completion

2012-03

Completion

2012-03

Drugs

Indications