Monitoring Exhaled Propofol to Individualize General Anesthesia

NCT01191021 ↗

Phase 1 Completed 20 enrolled University of California, San Francisco

NaSingle-groupSingle-blind

Summary

This trial investigates the relationship between concentrations of the anesthetic drug propofol in exhaled breath, blood and drug effect in volunteers undergoing general anesthesia. The main goal of this study is to develop a pharmacokinetic - and dynamic model for propofol in exhaled breath.

Timeline

Start: 2010-08
Primary completion: 2010-10
Completion: 2010-10

Publications

Background Hornuss C, Praun S, Villinger J, Dornauer A, Moehnle P, Dolch M, Weninger E, Chouker A, Feil C, Briegel J, Thiel M, Schelling G. Real-time monitoring of propofol in expired air in humans undergoing total intravenous anesthesia. Anesthesiology. 2007 Apr;106(4):665-74. doi: 10.1097/01.anes.0000264746.01393.e0.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Propofol	Small molecule	—	—

Indications

No indication recorded.