drugset / Trial / NCT01198912

Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trial

NCT01198912

Phase 2 Completed 33 enrolled University Hospital, Ghent
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a randomized, double blind, placebo controlled, parallel group, study in patients with chronic rhinosinusitis with or without nasal polyps. The objective is to test the clinical efficacy of long-term low dose oral doxycycline on wound healing quality after endoscopic sinus surgery.

Timeline

Start
2011-11-22
Primary completion
2016-09-06
Completion
2017-02-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Doxycycline Small molecule 100 mg Oral