A Study to Evaluate the Dosing of AMG 827 for Subjects With Inadequately Controlled Asthma

Summary

The purpose of this study is to determine if AMG 827 is effective compared to placebo as measured by change in Asthma Control Questionnaire (ACQ) composite scores.

Timeline

Start

2010-10-04

Primary completion

2011-12-21

Completion

2011-12-21

Publications

• Background Busse WW, Holgate S, Kerwin E, Chon Y, Feng J, Lin J, Lin SL. Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma. Am J Respir Crit Care Med. 2013 Dec 1;188(11):1294-302. doi: 10.1164/rccm.201212-2318OC.

Drugs

Indications