drugset
drugset / Trial / NCT01199380

Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms

NCT01199380 ↗

Phase 2 Completed 184 enrolled University of Maryland, College Park National Institute on Drug Abuse (NIDA) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

Depression related vulnerabilities are highly comorbid with smoking behavior and dramatically reduce cessation rates among both community and clinical samples. Previous research has examined the efficacy of cognitive-behavioral treatment for individuals with a history of major depressive disorder (MDD) in standard cessation treatment. A broader health impact can be achieved by targeting individuals with current elevated depressive symptoms to address their association with cessation failure. Thus the objective of the present proposal is to conduct a Stage II randomized controlled trial (RCT) comparing the behavioral activation intervention to standard treatment among a similar community sample of 200 adult smokers with elevated depressive symptoms. Participants will be followed over 52 weeks post-quit date and the larger sample size will allow for more complex analysis of cessation outcomes.

Timeline

Start
2010-09
Primary completion
2016-05
Completion
2016-05

Drugs

EvaluationDrugModalityDoseRoute
Background Nicotine Unknown 7 mg Other
Background Nicotine Unknown 14 mg Other
Background Nicotine Unknown 21 mg Other

Indications

No indication recorded.