drugset / Trial / NCT01205126
An Efficacy and Safety Study of Oral Osmotic Therapeutic System (OROS) Hydromorphone Hydrochloride (HCl) in Participants With Cancer Related Pain
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to compare the safety and efficacy of Oral Osmotic Therapeutic System (OROS) hydromorphone hydrochloride (HCl) with controlled-release oxycodone HCl in participants with cancer-related pain.
Timeline
- Start
- 2009-12
- Primary completion
- 2011-02
- Completion
- 2011-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydromorphone | Other / unclassified | 8 mg | Oral |
| Subject | Hydromorphone | Other / unclassified | 16 mg | Oral |
| Subject | Hydromorphone | Other / unclassified | 24 mg | Oral |
| Subject | Hydromorphone | Other / unclassified | 32 mg | Oral |
| Comparator | Oxycodone | Other / unclassified | 10 mg | — |
| Comparator | Oxycodone | Other / unclassified | 20 mg | — |
| Comparator | Oxycodone | Other / unclassified | 30 mg | — |
| Comparator | Oxycodone | Other / unclassified | 40 mg | — |
Indications
No indication recorded.