drugset / Trial / NCT01205646
PET Scanning to Evaluate Zoledronate Efficacy in Metastatic Prostate Cancer
Completed
11 enrolled
Barbara Ann Karmanos Cancer Institute
United States Department of Defense · collab
NaSingle-groupOpen-labelScreening
Summary
The primary goal for this trial is to assess the change in PET scans with the administration of zoledronate (bisphosphonate) therapy in patients with metastatic prostate cancer. It has been established that zoledronate therapy may play a role in delaying and reducing the incidence of skeletal events. Researchers propose to evaluate the change in the uptake value of FMAU PET scan after the zoledronate therapy. It has been demonstrated that FMAU PET scans can successfully demonstrate and detect bony metastatic sites in prostate cancer. In addition, investigators would like to evaluate the change in the level of the prostate-specific antigen (PSA) in the patient as well as outcome of bone scans.
Timeline
- Start
- 2010-09
- Primary completion
- 2013-08
- Completion
- 2015-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Zoledronate | Other / unclassified | 4 mg | Intravenous |