drugset / Trial / NCT01206036

CESAR Study in Prostate Cancer With Temsirolimus Added to Standard Docetaxel Therapy (CEPTAS)

NCT01206036

NaSingle-groupOpen-labelTreatment

Summary

In this Phase I study safety of the combination of Docetaxel and Temsirolimus needs to be shown before the study can be expanded into a Phase II study to examine the activity of a safe combination of Temsirolimus and Docetaxel in a comparison with Docetaxel alone.

Timeline

Start
2010-07
Primary completion
2014-09
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 60 mg/m2
Subject Docetaxel Small molecule 75 mg/m2
Subject Temsirolimus Small molecule 15 mg
Subject Temsirolimus Small molecule 25 mg

Indications