drugset / Trial / NCT01206036
CESAR Study in Prostate Cancer With Temsirolimus Added to Standard Docetaxel Therapy (CEPTAS)
NaSingle-groupOpen-labelTreatment
Summary
In this Phase I study safety of the combination of Docetaxel and Temsirolimus needs to be shown before the study can be expanded into a Phase II study to examine the activity of a safe combination of Temsirolimus and Docetaxel in a comparison with Docetaxel alone.
Timeline
- Start
- 2010-07
- Primary completion
- 2014-09
- Completion
- 2015-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Docetaxel | Small molecule | 60 mg/m2 | — |
| Subject | Docetaxel | Small molecule | 75 mg/m2 | — |
| Subject | Temsirolimus | Small molecule | 15 mg | — |
| Subject | Temsirolimus | Small molecule | 25 mg | — |