drugset / Trial / NCT01207895

Molecular Determinants Affecting Fluoro-L-thymidine (FLT) Positron Emission Tomography (PET) in Rectal Cancer

NCT01207895 ↗

Phase 1 Completed 5 enrolled Vanderbilt-Ingram Cancer Center
NaSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to determine if positron emission tomography (PET) imaging with an imaging agent called 18F-fluorodeoxythymidine(\[18F\]-FLT) will allow investigators to measure how well tumor(s) respond to treatment without taking a tissue sample (biopsy). Additionally, the investigators want to determine if it is possible to predict how well tumor(s) might respond to treatment with \[18F\]-FLT PET imaging.

Timeline

Start
2010-03
Primary completion
2012-12
Completion
2013-07

Drugs

EvaluationDrugModalityDoseRoute
Subject 18F-fluorodeoxythymidine Diagnostic / imaging agent — Intravenous

Indications