drugset / Trial / NCT01209676

IMCgp100 in Advanced Unresectable Melanoma

NCT01209676

Phase 0 Completed 1 enrolled University of Pennsylvania
NaSingle-groupOpen-labelTreatment

Summary

A phase 0, exploratory study of the pharmacodynamics of a single intratumoral dose of IMCgp100, a monoclonal T cell receptor anti-CD3 scFv fusion protein, in subjects with advanced unresectable melanoma to assess the safety and pharmacodynamic properties of single intratumoral doses of IMCgp100 in the setting of advanced unresectable melanoma. Six patients will be enrolled to complete the study over approximately 12-15 months.

Timeline

Start
2010-09
Primary completion
2013-03
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Tebentafusp Protein / enzyme biologic 0.00017 mg Other
Subject Tebentafusp Protein / enzyme biologic 0.0017 mg Other

Indications