The Effects of Atorvastatin on the Nitric Oxide-system in Healthy Young Man

Summary

It has been documented that statin reduce mortality and morbidity in patients with cardiovascular disease. This effect can partly be related to a reduction in cholesterol levels in blood. Nitric oxide (NO) production is reduced in several chronic diseases such as nephropathy, diabetes and hypertension. The purpose of this study is to investigate the effect of Atorvastatin treatment on the NO-system measuring renal and cardiovascular variables in healthy man.

Timeline

Start

2010-05

Primary completion

2011-06

Completion

2011-06

Drugs

Indications