drugset

drugset / Trial / NCT01216293

Effect of Dexlansoprazole on Bone Homeostasis

NCT01216293 ↗

Phase 1 Completed 115 enrolled Takeda

RandomizedParallel-groupQuadruple-blindOther

Summary

The purpose of this study is to evaluate the effect of dexlansoprazole modified release (MR), once daily (QD), on bone homeostasis.

Timeline

Start: 2010-11-01
Primary completion: 2014-08-01
Completion: 2015-02-01

Publications

Hansen KE, Nieves JW, Nudurupati S, Metz DC, Perez MC. Dexlansoprazole and Esomeprazole Do Not Affect Bone Homeostasis in Healthy Postmenopausal Women. Gastroenterology. 2019 Mar;156(4):926-934.e6. doi: 10.1053/j.gastro.2018.11.023. Epub 2018 Nov 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexlansoprazole	Other / unclassified	60 mg	Oral
Comparator	Esomeprazole	Small molecule	40 mg	Oral

Indications