drugset / Trial / NCT01217229

Safety and Efficacy Study of PLX3397 in Adults With Relapsed or Refractory Hodgkin Lymphoma

NCT01217229

Phase 2 Completed 20 enrolled Daiichi Sankyo Plexxikon · collab
NaSingle-groupOpen-labelTreatment

Summary

PLX3397 is a selective inhibitor of Fms, Kit, and oncogenic Flt3 activity.The primary objective of this study is to evaluate the efficacy, as measured by overall response rate, of orally administered PLX3397 in patients with relapsed or refractory classical Hodgkin lymphoma (HL). Secondary objectives include safety, the duration of response, the disease control rate, progression free survival, and how the drug affects your body.

Timeline

Start
2011-03-03
Primary completion
2012-04-26
Completion
2012-04-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Pexidartinib Small molecule 900 mg Oral
Subject Pexidartinib Small molecule 1200 mg Oral