drugset / Trial / NCT01217229
Safety and Efficacy Study of PLX3397 in Adults With Relapsed or Refractory Hodgkin Lymphoma
NaSingle-groupOpen-labelTreatment
Summary
PLX3397 is a selective inhibitor of Fms, Kit, and oncogenic Flt3 activity.The primary objective of this study is to evaluate the efficacy, as measured by overall response rate, of orally administered PLX3397 in patients with relapsed or refractory classical Hodgkin lymphoma (HL). Secondary objectives include safety, the duration of response, the disease control rate, progression free survival, and how the drug affects your body.
Timeline
- Start
- 2011-03-03
- Primary completion
- 2012-04-26
- Completion
- 2012-04-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pexidartinib | Small molecule | 900 mg | Oral |
| Subject | Pexidartinib | Small molecule | 1200 mg | Oral |