drugset / Trial / NCT01220570
The Growth Factor Signature (GFS) as an Intermediate Biomarker of Response for Development of PI3K-Pathway Inhibitors in Patients With Breast Cancer (MK-8669-050)
RandomizedParallel-groupOpen-labelTreatment
Summary
This clinical trial will evaluate whether treatment with ridaforolimus, dalotuzumab, or ridforolimus/dalotuzumab combination therapy reduces Growth Factor Signature (GFS) Score among participants with breast cancer.
Timeline
- Start
- 2010-09
- Primary completion
- 2012-12
- Completion
- 2012-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | dalotuzumab | Monoclonal antibody | 10 mg/kg | Intravenous |
| Subject | ridaforolimus | Small molecule | 40 mg | — |