drugset / Trial / NCT01221259

A Randomized, Double-blind, Placebo-controlled, Sequential Ascending, Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2212 in Healthy Subjects

NCT01221259 ↗

Phase 1 Completed 60 enrolled Eisai Inc.
RandomizedSingle-groupTriple-blindTreatment

Summary

This study is designed as a single ascending dose study in healthy subjects to evaluate safety, tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) in plasma and Cerebrospinal (CSF) following single oral doses of E2212.

Timeline

Start
2010-01
Primary completion
2011-10
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Subject E2212 Small molecule 10 mg Oral
Subject E2212 Small molecule 250 mg Oral

Indications