drugset / Trial / NCT01221259
A Randomized, Double-blind, Placebo-controlled, Sequential Ascending, Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2212 in Healthy Subjects
RandomizedSingle-groupTriple-blindTreatment
Summary
This study is designed as a single ascending dose study in healthy subjects to evaluate safety, tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) in plasma and Cerebrospinal (CSF) following single oral doses of E2212.
Timeline
- Start
- 2010-01
- Primary completion
- 2011-10
- Completion
- 2012-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | E2212 | Small molecule | 10 mg | Oral |
| Subject | E2212 | Small molecule | 250 mg | Oral |