drugset / Trial / NCT01222026
Systematic Treatment After Successful Surgical Treatment for Primary Hyperparathyroidism With Strontium Ranelate
RandomizedParallel-groupTriple-blindTreatment
Summary
Patients with primary hyperparathyroidism (pHPT) with osteopenia and osteoporosis are treated with strontium ranelate/Ca+Vitamin-D or placebo/Ca+Vitamin D after successful surgical treatment of pHPT. Strontium ranelate/Ca + Vitamin-D helps to regain bone mass in patients with osteopenia or osteoporosis after successful parathyroidectomy for pHPT and results in higher gain of BMD than placebo treated patients.
Timeline
- Start
- 2010-09
- Primary completion
- 2014-12
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Strontium Ranelate | Small molecule | 2 g | — |
| Comparator | Calcium carbonate | Other / unclassified | 1000 mg | — |
| Comparator | Vitamin D | Other / unclassified | 800 iu | — |