drugset / Trial / NCT01222689

Selumetinib and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

NCT01222689

Phase 2 Completed 46 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well giving selumetinib and erlotinib hydrochloride together works in treating patients with locally advanced or metastatic pancreatic cancer that is refractory to chemotherapy. Selumetinib and erlotinib hydrochloride may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2010-11
Primary completion
2013-04
Completion
2014-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Erlotinib Small molecule Oral
Subject Selumetinib Small molecule Oral