drugset / Trial / NCT01222819

SubCutaneous (SC) Versus Intravenous (IV) Granulocyte Colony Stimulating Factors (G-CSF) for the Treatment of Neutropenia in Hospitalized Haemato-oncological Patients

NCT01222819

Phase 4 Terminated 120 enrolled Rabin Medical Center
RandomizedParallel-groupOpen-labelTreatment

Summary

Granulocyte colony stimulating factor (G-CSF) is frequently used among patients with cancer including those with haematological malignancies. Filgrastim is a recombinant human CSF whose biological activity is similar to that of endogenous G-CSF. In the treatment of chemotherapy-induced neutropenia in patients with various types of cancer CSFs significantly reduced the time to neutrophil recovery and length of hospitalization.

Timeline

Start
2011-01
Primary completion
2012-12
Completion
2013-04

Drugs

EvaluationDrugModalityDoseRoute
Subject filgrastim Protein / enzyme biologic 5 ug/kg Intravenous
Subject filgrastim Protein / enzyme biologic 300 ug Intravenous
Subject filgrastim Protein / enzyme biologic 480 ug Intravenous

Indications