drugset / Trial / NCT01222819
SubCutaneous (SC) Versus Intravenous (IV) Granulocyte Colony Stimulating Factors (G-CSF) for the Treatment of Neutropenia in Hospitalized Haemato-oncological Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
Granulocyte colony stimulating factor (G-CSF) is frequently used among patients with cancer including those with haematological malignancies. Filgrastim is a recombinant human CSF whose biological activity is similar to that of endogenous G-CSF. In the treatment of chemotherapy-induced neutropenia in patients with various types of cancer CSFs significantly reduced the time to neutrophil recovery and length of hospitalization.
Timeline
- Start
- 2011-01
- Primary completion
- 2012-12
- Completion
- 2013-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | filgrastim | Protein / enzyme biologic | 5 ug/kg | Intravenous |
| Subject | filgrastim | Protein / enzyme biologic | 300 ug | Intravenous |
| Subject | filgrastim | Protein / enzyme biologic | 480 ug | Intravenous |