drugset / Trial / NCT01222949
A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™
Phase 1
Completed
80 enrolled
sigma-tau i.f.r. S.p.A.
CPR Pharma Services Pty Ltd, Australia · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The Study was designed to evaluate the pharmacokinetics of DHA and PQ in healthy volunteers and to assess the effect of ethnicity (Asian vs Caucasian), gender and body weight on the relative bioavailability of DHA and PQ.
Timeline
- Start
- 2010-02
- Primary completion
- 2010-07
- Completion
- 2010-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dihydroartemisinin-piperaquine | Unknown | 40 mg | — |
| Subject | Dihydroartemisinin-piperaquine | Unknown | 320 mg | — |