drugset / Trial / NCT01226628

A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degeneration

NCT01226628 ↗

Phase 1/2 Completed 39 enrolled Janssen Research & Development, LLC
RandomizedParallel-groupOpen-labelTreatment

Summary

The main purpose of this study to evaluate the safety and tolerability of CNTO 2476 administered subretinally (beneath the retina) using the iTrack Model 275 micro catheter in patients with visual acuity (acuteness or clearness of vision) impairment associated with the geographic atrophy (GA: partial or complete wasting away of retinal layer below the retina) manifestation of age-related macular degeneration (AMD: medical condition which usually affects older adults and results in a loss of vision in the center of the visual field \[the macula\] because of damage to the retina).

Timeline

Start
2010-10-21
Primary completion
2015-03-31
Completion
2017-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject CNTO 2476 Cell therapy 60000 cells Other
Subject CNTO 2476 Cell therapy 120000 cells Other
Subject CNTO 2476 Cell therapy 300000 cells Other
Subject CNTO 2476 Cell therapy 560000 cells Other