drugset

drugset / Trial / NCT01228903

Uric Acid and the Endothelium in CKD

NCT01228903 ↗

Completed 80 enrolled University of Colorado, Denver National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab National Institutes of Health (NIH) · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

This study will test the hypothesis that uric acid impairs the function of vessels in patients with kidney disease

Timeline

Start: 2010-10
Primary completion: 2016-09
Completion: 2016-09

Publications

Perrenoud L, Kruse NT, Andrews E, You Z, Chonchol M, Wu C, Ten Eyck P, Zepeda-Orozco D, Jalal D. Uric Acid Lowering and Biomarkers of Kidney Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney Med. 2020 Feb 26;2(2):155-161. doi: 10.1016/j.xkme.2019.11.007. eCollection 2020 Mar-Apr.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Allopurinol	Small molecule	300 mg	—

Indications