Clinical Pharmacology of Aliskiren in Combination With Cyclosporine in Cardiac Transplantation

Summary

The purpose of this study is to evaluate the safety and efficacy of the blood pressure medication, aliskiren, in heart transplant patients. In terms of safety, the investigators will evaluate the blood levels of aliskiren and determine if aliskiren alters the blood levels of the anti-rejection medication, cyclosporine, in these patients. In terms of efficacy, the investigators will determine how well aliskiren lowers blood pressure in heart transplant patients.

Timeline

Start

2011-05

Primary completion

2012-12

Completion

2012-12

Drugs

Indications