Oxytocin in Cesarean Delivery

Summary

In this study the investigators hypothesize that infused combinations of oxytocin and ergometrine will exhibit fewer cardiac and neurological side effects than equipotent infusion of oxytocin alone. In order to perform this study the investigators perform the following steps: 1. The investigators validate a quantitative measure of uterine tone as our primary endpoint. 2. The investigators use this endpoint measure in order to determine equipotential doses of different tocotonic drug regimens, based on the ED50 for each. 3. Using equipontial ratios based on the ED50, the investigators compare hemodynamic and other side effects of these tocotonic drug regimes. Plasma levels of oxytocin will be measured.

Timeline

Start

2010-11

Primary completion

2011-05

Completion

2011-05

Drugs

Indications

No indication recorded.