drugset / Trial / NCT01236638

Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)

NCT01236638

Phase 2 Completed 120 enrolled Sierra Oncology LLC - a GSK company
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This extension protocol to the core study CCL09101 allows patients who have tolerated the drug and derived a clinical benefit, to continue to receive treatment beyond the 9 cycles of the core protocol. Long term safety and efficacy of CYT387 (momelotinib) will be evaluated.

Timeline

Start
2010-11
Primary completion
2014-06
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Momelotinib Small molecule 150 mg Oral
Subject Momelotinib Small molecule 400 mg Oral