Reduction of Postherpetic Neuralgia in Herpes Zoster

Completed 133 enrolled Center for Clinical Studies, Texas

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The addition of gabapentin therapy to standard antiviral treatment with valacyclovir in acute herpes zoster patients will decrease the incidence of post-herpetic neuralgia.

Timeline

Start: 2002-02
Primary completion: 2007-10
Completion: 2007-10

Publications

Lapolla W, Digiorgio C, Haitz K, Magel G, Mendoza N, Grady J, Lu W, Tyring S. Incidence of postherpetic neuralgia after combination treatment with gabapentin and valacyclovir in patients with acute herpes zoster: open-label study. Arch Dermatol. 2011 Aug;147(8):901-7. doi: 10.1001/archdermatol.2011.81. Epub 2011 Apr 11.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Gabapentin	Small molecule	3600 mg	—
Background	Valacyclovir	Unknown	1000 mg	—

Reduction of Postherpetic Neuralgia in Herpes Zoster

Summary

Timeline

Publications

Drugs

Indications