Effect of Niacin on Transport of HDL and Relationship to Atherogenic Lipoproteins and Lipolysis

Summary

This study looks at whether niacin improves reverse cholesterol transport (RCT) in healthy volunteers. 3H-Cholesterol will be used to measure RCT by analyzing changes in the tracer activity in total plasma, lipoproteins, red blood cells (RBCs) and stool. The hypothesis is that niacin augments reverse cholesterol transport.

Timeline

Start

2010-11

Primary completion

2011-05

Completion

2011-05

Drugs

Indications