drugset / Trial / NCT01251731
Single and Multiple Dose Asian Bridging Study
RandomizedCrossoverQuadruple-blindTreatment
Summary
The purpose of this study is to evaluate the single-dose (SD) pharmacokinetics (PK), pharmacodynamics (PD), safety and tolerability of 10, 40, and 80 mg E5501 followed by a selected dose for multiple dosing (MD) in healthy Japanese, Chinese, and Caucasian subjects.
Timeline
- Start
- 2010-07
- Primary completion
- 2011-01
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Avatrombopag | Small molecule | 10 mg | Oral |
| Subject | Avatrombopag | Small molecule | 40 mg | Oral |
| Subject | Avatrombopag | Small molecule | 80 mg | Oral |
Indications
No indication recorded.