drugset / Trial / NCT01253278

A Multiple-Ascending Dose Study in Type 2 Diabetes Mellitus Patients

NCT01253278 ↗

Phase 1 Completed 38 enrolled Eli Lilly and Company
RandomizedParallel-groupDouble-blind

Summary

The study drug LY2393910 is being evaluated as a possible treatment for diabetes. The primary purpose of a patient's participation in this study is to help answer the following research question(s), and not to provide treatment for diabetes: * The safety of LY2393910 and any side effects that might be associated with it following 2 weeks of doses * How long it takes the body to absorb and remove LY2393910 following dosing over 2 weeks * How daily dosing of LY2393910 affects blood levels of sugar (glucose), insulin and other naturally occurring substances in your body * How daily dosing of LY2393910 affects the cells that produce insulin * Any differences in the above between LY2393910 taken as daily doses in the morning or in the evening

Timeline

Start
2010-03
Primary completion
2011-05
Completion
2011-05

Drugs

EvaluationDrugModalityDoseRoute
Subject LY2393910 Unknown 20 mg Oral
Subject LY2393910 Unknown 60 mg Oral
Subject LY2393910 Unknown 150 mg Oral
Subject LY2393910 Unknown 450 mg Oral