drugset / Trial / NCT01257581
Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
Phase 2
Completed
60 enrolled
Nazem Atassi
ALS Therapy Alliance · collabState University of New York - Upstate Medical University · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of the study is to evaluate the safety and efficacy of high dose creatine and two dosages of tamoxifen treatment in amyotrophic lateral sclerosis (ALS).
Timeline
- Start
- 2011-03
- Primary completion
- 2012-12
- Completion
- 2013-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Creatine | Other / unclassified | 30 g | Oral |
| Subject | Tamoxifen | Small molecule | 40 mg | Oral |
| Subject | Tamoxifen | Small molecule | 80 mg | Oral |