Llama Antibody, Rotavirus Diarrhoea, Children

Summary

The investigators hypothesize that : oral administration of VHH batch 203027 will be * safe and tolerable for healthy Bangladeshi humans of all age groups (Part I) * effective in reducing severity of diarrhoea in children with proven rotavirus infection (Part II). This entry only covers Part II.

Timeline

Start

2006-01

Primary completion

2008-09

Completion

2009-11

Publications

• Sarker SA, Jakel M, Sultana S, Alam NH, Bardhan PK, Chisti MJ, Salam MA, Theis W, Hammarstrom L, Frenken LG. Anti-rotavirus protein reduces stool output in infants with diarrhea: a randomized placebo-controlled trial. Gastroenterology. 2013 Oct;145(4):740-748.e8. doi: 10.1053/j.gastro.2013.06.053. Epub 2013 Jul 2.

Drugs

Indications