drugset / Trial / NCT01269476

Safety and Pharmacokinetics of SNX-001 in Healthy Aged Volunteers

NCT01269476 ↗

Phase 1 Completed 27 enrolled SeneXta Therapeutics SA
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a randomised, double-blind, group-sequential, placebo-controlled, safety and pharmacokinetic study in healthy, aged volunteers. Objectives: 1. to confirm the previously reported safety profile of oral SNX-001 after single and multiple doses of 3.6, 7.2 or 10.8 mg compared to placebo 2. to establish SNX-001 pharmacokinetic profile.

Timeline

Start
2009-12
Primary completion
2010-06
Completion
2010-08

Drugs

EvaluationDrugModalityDoseRoute
Subject METHANESULFONYL FLUORIDE Small molecule 3.6 mg Oral
Subject METHANESULFONYL FLUORIDE Small molecule 7.2 mg Oral
Subject METHANESULFONYL FLUORIDE Small molecule 10.8 mg Oral

Indications

No indication recorded.