drugset / Trial / NCT01269762
Pharmacokinetic and Drug Interaction Study of Red Yeast Rice Capsules
Phase 4
Completed
14 enrolled
National Taiwan University Hospital
National Science and Technology Council, Taiwan · collab
Non-randomizedCrossoverOpen-labelTreatment
Summary
Red yeast rice capsule (LipoCol Forte)is a nature product that has been demonstrated a significant cholesterol lowering effect which might be caused by addictive and/or synergistic effects of lovastatin (monacolin K) with other monacolins and substances in capsules. The usual dose of red yeast rice capsule(LipoCol Forte)for hypercholesterolemia is one capsule twice/day. However, the pharmacokinetic profile of red yeast rice capsule (LipoCol Forte)is still unknown. The objective of the study is to evaluate the pharmacokinetic profile of red yeast rice capsule (LipoCol Forte) after administering single and multiple dose to healthy subjects.
Timeline
- Start
- 2011-01
- Primary completion
- 2011-04
- Completion
- 2011-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LipoCol Forte | Unknown | 600 mg | — |
| Subject | LipoCol Forte | Unknown | 1200 mg | — |
| Subject | LipoCol Forte | Unknown | 2400 mg | — |
Indications
No indication recorded.