The Effects of Short-Term Exenatide Therapy in Newly Diagnosed Type 2 Diabetic Patients

Summary

Whether GLP-1 and GLP-1 receptor agonists will produce a sustained improvement in beta-cell function following short-term therapy is currently not known. This randomized, controlled trial is carried to assess the efficacy of short-term insulin therapy (NPH injection twice daily) compared with GLP-1 analogue (Exenatide injection twice daily) on glycemic control, remission rate, ß-cell function, and long-term glycemic control in newly diagnosed type 2 diabetic patients with moderate hyperglycemia.

Timeline

Start

2010-11

Primary completion

2014-12

Completion

2015-12

Drugs

Indications