Clozapine/Paliperidone Versus Clozapine/Placebo in Resistant Schizophrenia

Summary

augmentation of clozapine with paliperidone in the treatment of resistant schizophrenia has not been tested until now in randomized controlled trials. This combination is supposed to have therapeutic efficacy in the treatment of resistant schizophrenia.

Timeline

Start

2009-01

Primary completion

2009-10

Completion

2009-12

Publications

• Background Mortimer AM, Singh P, Shepherd CJ, Puthiryackal J. Clozapine for treatment-resistant schizophrenia: National Institute of Clinical Excellence (NICE) guidance in the real world. Clin Schizophr Relat Psychoses. 2010 Apr;4(1):49-55.

Drugs

Indications