drugset / Trial / NCT01281306
An 8-week Study to Evaluate the Dose Response of AHU377 in Combination With Valsartan 320 mg in Patients With Mild-to-moderate Systolic Hypertension
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of the study is to evaluate dose response of blood pressure lowering for 4 doses of AHU377, given once daily (50 mg, 100 mg, 200 mg and 400 mg) in combination with a fixed dose of valsartan (320 mg).
Timeline
- Start
- 2011-01
- Primary completion
- 2011-12
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LCZ696 | Unknown | 400 mg | — |
| Subject | Sacubitril | Small molecule | 50 mg | — |
| Subject | Sacubitril | Small molecule | 100 mg | — |
| Subject | Sacubitril | Small molecule | 200 mg | — |
| Subject | Sacubitril | Small molecule | 400 mg | — |
| Subject | Valsartan | Small molecule | 320 mg | — |