drugset / Trial / NCT01281306

An 8-week Study to Evaluate the Dose Response of AHU377 in Combination With Valsartan 320 mg in Patients With Mild-to-moderate Systolic Hypertension

NCT01281306

Phase 2 Completed 910 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of the study is to evaluate dose response of blood pressure lowering for 4 doses of AHU377, given once daily (50 mg, 100 mg, 200 mg and 400 mg) in combination with a fixed dose of valsartan (320 mg).

Timeline

Start
2011-01
Primary completion
2011-12
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject LCZ696 Unknown 400 mg
Subject Sacubitril Small molecule 50 mg
Subject Sacubitril Small molecule 100 mg
Subject Sacubitril Small molecule 200 mg
Subject Sacubitril Small molecule 400 mg
Subject Valsartan Small molecule 320 mg

Indications