drugset / Trial / NCT01285102

Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer

NCT01285102 ↗

Phase 1 Terminated 4 enrolled Fox Chase Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as irinotecan hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or stopping them from dividing. Chemoembolization kills tumor cells by blocking blood flow to the tumor and keeping chemotherapy drugs near the tumor. PURPOSE: This phase II trial is studying how well chemoembolization using irinotecan works in treating patients with liver metastases from metastatic colon or rectal cancer.

Timeline

Start
2010-10
Primary completion
2011-12
Completion
2013-01

Outcome

Outcome not reported

Stopped: “This study was closed early by the DSMB due to increased toxicity.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule 50 mg Other
Subject Irinotecan Small molecule 75 mg Other
Subject Irinotecan Small molecule 100 mg Other