Safety Study of Transmyocardial Revascularization (TMR) With Bone Marrow Aspirate (BMAC) for Angina Reduction

Terminated 7 enrolled Cardiogenesis Corporation, a wholly-owned subsidiary of CryoLife, Inc.

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the safety of injecting autologous bone marrow concentrate with laser transmyocardial revascularization (TMR) for treatment of angina which cannot be treated by direct coronary intervention.

Timeline

Start: 2010-10
Primary completion: 2012-03
Completion: 2012-03

Publications

Background Reyes G, Allen KB, Aguado B, Duarte J. Bone marrow laser revascularisation for treating refractory angina due to diffuse coronary heart disease. Eur J Cardiothorac Surg. 2009 Jul;36(1):192-4. doi: 10.1016/j.ejcts.2009.03.022. Epub 2009 Apr 25.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bone Marrow Aspirate Concentrate	Cell therapy	18 ml	Other

Safety Study of Transmyocardial Revascularization (TMR) With Bone Marrow Aspirate (BMAC) for Angina Reduction

Summary

Timeline

Publications

Drugs

Indications