Ulimorelin Study of Efficacy and Safety (ULISES 007)

Summary

Post-operative administration of ulimorelin is expected to reduce time to recovery of Gastrointestinal (GI) function in patients who have undergone partial large bowel resection.

Timeline

Start

2011-01

Primary completion

2012-01

Completion

2012-01

Outcome

Missed primary endpoint

paper Although the efficacy of ulimorelin in reducing the duration of postoperative ileus was not demonstrated in these studies PMID 23739196 ↗

Publications

• Shaw M, Pediconi C, McVey D, Mondou E, Quinn J, Chamblin B, Rousseau F. Safety and efficacy of ulimorelin administered postoperatively to accelerate recovery of gastrointestinal motility following partial bowel resection: results of two randomized, placebo-controlled phase 3 trials. Dis Colon Rectum. 2013 Jul;56(7):888-97. doi: 10.1097/DCR.0b013e31829196d0.

Drugs

Indications