drugset / Trial / NCT01286051
Single Injection of Ganirelix in Gonadotropin Intrauterine Insemination (IUI) Cycles
RandomizedParallel-groupOpen-labelTreatment
Summary
Ovulation induction (OI) using gonadotropins is one of the most widely prescribed treatments of infertility. One common problem encountered while attempting OI using gonadotropins is premature ovulation. The purpose of this study is to examine the effect of a single injection of a medication, called ganirelix, to prevent premature ovulation. Patients will be divided into two groups. In the first group, gonadotropins will be used to stimulate the ovaries. In the second group gonadotropins will be used in addition to a single injection of ganirelix, a gonadotropin releasing hormone (GnRH) antagonist. Pregnancy rates will be compared between groups.
Timeline
- Start
- 2011-01
- Primary completion
- 2012-09
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ganirelix | Protein / enzyme biologic | 250 ug | Subcutaneous |
| Comparator | Follitropin beta | Protein / enzyme biologic | 75 iu | — |
| Comparator | Follitropin beta | Protein / enzyme biologic | 150 iu | — |
Indications
No indication recorded.