drugset / Trial / NCT01299610

A Study to Test the Effect of 2 Different Doses of Topical GW870086X on Atopic Dermatitis Also Including a Postive Control and a Placebo

NCT01299610

Phase 2 Completed 25 enrolled GlaxoSmithKline
RandomizedCrossoverDouble-blindTreatment

Summary

This study is a randomised, double-blind, placebo-controlled study to assess the efficacy of GW870086X cream formulation in subjects with moderate to severe atopic dermatitis. Subjects will be assigned to take 3 out of the 4 possible treatments for 21 ±2 days: GW870086X 0.2% cream, GW870086X 2% cream, FP 0.05% cream (as a positive control) and placebo cream. All subjects will be randomised to receive placebo cream. Three index lesions located on the arms and/or legs (one on each) will be identified per subject and each treatment will be applied to the same lesion.

Timeline

Start
2010-12-01
Primary completion
2011-03-01
Completion
2011-04-14

Drugs

EvaluationDrugModalityDoseRoute
Subject FP Unknown 0.05 % Topical
Subject GW870086 Small molecule 0.2 % Topical
Subject GW870086 Small molecule 2 % Topical

Indications