drugset / Trial / NCT01300468

Study of PHA-848125AC in Adult Patients With Advanced/Metastatic Solid Tumors

NCT01300468 ↗

Phase 1 Completed 38 enrolled Nerviano Medical Sciences
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this open-label, multi center, Phase I study was to determine the safety profile of the oral compound PHA-848125AC administered according to two different schedules of administrations to advanced/metastatic solid tumor patients. Objectives of the study were to determine the maximum tolerated dose and the dose that can be recommended for Phase II investigations.

Timeline

Start
2006-04
Primary completion
2009-05
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Milciclib Small molecule — Oral

Indications