drugset / Trial / NCT01304602
A Trial of Irinotecan and BKM120 in Previously Treated Advanced Colorectal Cancer
NaSingle-groupOpen-labelTreatment
Summary
This phase I trial will use the combination of irinotecan and BKM120 in patients with advanced colorectal cancer who have failed on or have become intolerant of at least one line of therapy for advanced colorectal cancer and who are candidates for irinotecan therapy.
Timeline
- Start
- 2011-02
- Primary completion
- 2014-04
- Completion
- 2015-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Buparlisib | Small molecule | — | Oral |
| Subject | Irinotecan | Small molecule | — | Intravenous |