drugset / Trial / NCT01310296
Lofexidine ADME & Mass Balance in Volunteers
Phase 1
Completed
12 enrolled
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA) · collab
RandomizedCrossoverOpen-labelBasic science
Summary
The purpose of this study is to determine the mass balance and absolute bioavailability of a single oral dose of 14C-labeled lofexidine compared to a single intravenous dose of lofexidine.
Timeline
- Start
- 2011-07
- Primary completion
- 2011-08
- Completion
- 2011-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lofexidine | Small molecule | 200 ug | Oral |
| Subject | Lofexidine | Small molecule | 400 ug | Oral |
Indications
No indication recorded.