drugset / Trial / NCT01314482
Minocycline for the Prevention of Post-operative Intercostal Neuralgia
RandomizedParallel-groupDouble-blindTreatment
Summary
In about half the patients who have an open chest surgery there is persistent severe pain in the chest. The investigators are examining whether minocycline, a commonly used antibiotic, will prevent pain. Minocycline blocks the activity of immune cells which the investigators believe are responsible for prolonging the pain.
Timeline
- Start
- 2010-11
- Primary completion
- 2013-12
- Completion
- 2014-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Minocycline | Small molecule | 200 mg | — |
Indications
No indication recorded.