drugset / Trial / NCT01323933

First-in-human Study of AB0024 to Evaluate Safety and Tolerability in Adults With Advanced Solid Tumors

NCT01323933

Phase 1 Completed 32 enrolled Gilead Sciences
NaSingle-groupOpen-labelTreatment

Summary

Analysis of safety, tolerability, and PK data will provide information that will guide future development of AB0024.

Timeline

Start
2010-06
Primary completion
2012-03
Completion
2012-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Simtuzumab Monoclonal antibody 1 mg/kg Intravenous
Subject Simtuzumab Monoclonal antibody 3 mg/kg Intravenous
Subject Simtuzumab Monoclonal antibody 10 mg/kg Intravenous
Subject Simtuzumab Monoclonal antibody 20 mg/kg Intravenous

Indications