Role of the Endogenous Opioid System Underlying Modulation of Experimental Pain

Summary

The aim of this proposal is to characterize pain inhibition in healthy controls and Temporomandibular Disorder (TMD) patients with two models of endogenous pain modulation (off-set analgesia; conditioned pain modulation), and to investigate the function of the endogenous opioid system in these responses by using pharmacological blockade of the opioid receptor.

Timeline

Start

2011-12

Primary completion

2012-07

Completion

2012-07

Drugs

Indications