A Study to Compare Oxybutynin to a Placebo in Women and the Effect on Plantar Hyperhidrosis

Summary

A study in which the experimental treatment procedure is compared to a standard (control) treatment, The use of oxybutynin in the late postoperative thoracic sympathectomy for women: 1. To Evaluate the effect of oxybutynin on plantar hyperhidrosis. 2. To evaluate the effect of oxybutynin in compensatory hyperhidrosis. 3. To compare the results of questionnaires on quality of life and specific for hyperhidrosis to the results of TEWL.

Timeline

Start

2010-03

Primary completion

2010-05

Completion

2010-06

Publications

• Background Tupker RA, Harmsze AM, Deneer VH. Oxybutynin therapy for generalized hyperhidrosis. Arch Dermatol. 2006 Aug;142(8):1065-6. doi: 10.1001/archderm.142.8.1065. No abstract available.
• Background Mijnhout GS, Kloosterman H, Simsek S, Strack van Schijndel RJ, Netelenbos JC. Oxybutynin: dry days for patients with hyperhidrosis. Neth J Med. 2006 Oct;64(9):326-8.
• Costa Ada S Jr, Leao LE, Succi JE, Perfeito JA, Filho Castelo A, Rymkiewicz E, Filho Aurelio Marchetti M. Randomized trial - oxybutynin for treatment of persistent plantar hyperhidrosis in women after sympathectomy. Clinics (Sao Paulo). 2014 Feb;69(2):101-5. doi: 10.6061/clinics/2014(02)05.

Drugs

Indications