drugset / Trial / NCT01329042
Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis
Phase 4
Completed
80 enrolled
Ouiheng International Healthcare Co., Ltd
Chiang Mai University · collabChulalongkorn University · collabPrince Songkla University · collabSiriraj Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Extracorporeal shock wave lithotripsy (ESWL) and Percutaneous nephrolithotomy (PCNL) become the therapy of choice for renal stone. Although providing good results, stone recurrence is usually found as the therapies do not change the underlying metabolic abnormality. Among the metabolic disorders, hypocitraturia is an important risk factor for calcium nephrolithiasis. This study evaluate the preventive effects of potassium sodium citrate on stone recurrence as well as stone growth post ESWL or PCNL, in patients with calcium-containing stones.
Timeline
- Start
- 2005-05
- Primary completion
- 2007-10
- Completion
- 2008-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | POTASSIUM SODIUM HYDROGEN CITRATE ANHYDROUS | Small molecule | 81 meq | Oral |