drugset / Trial / NCT01332799
Xanthine Oxidase Inhibition in Renal Transplant Recipients
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Cardiovascular disease is the leading cause of mortality in kidney transplantation. The enzyme xanthine oxidase may play an important role in the cardiovascular disease of kidney transplant recipients. Inhibiting this enzyme with allopurinol may improve vascular health and protects against cardiovascular complications.
Timeline
- Start
- 2011-02
- Primary completion
- 2018-08-10
- Completion
- 2018-08-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Allopurinol | Small molecule | — | Oral |